Aldo-keto reductase 1B10 and its role in proliferation capacity of drug-resistant cancers

• Main Authors: Toshiyuki eMatsunaga (Author), Yasuhiro eWada (Author), Satoshi eEndo (Author), Midori eSoda (Author), Ossama eEl-kabbani (Author), Akira eHara (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2012-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The human aldo-keto reductase AKR1B10, originally identified as an aldose reductase-like protein and human small intestine aldose reductase, is a cytosolic NADPH-dependent reductase that metabolizes a variety of endogenous compounds, such as aromatic and aliphatic aldehydes and dicarbonyl compounds,...