Aldo-keto reductase 1B10 and its role in proliferation capacity of drug-resistant cancers

• Egile Nagusiak: Toshiyuki eMatsunaga (Egilea), Yasuhiro eWada (Egilea), Satoshi eEndo (Egilea), Midori eSoda (Egilea), Ossama eEl-kabbani (Egilea), Akira eHara (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2012-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The human aldo-keto reductase AKR1B10, originally identified as an aldose reductase-like protein and human small intestine aldose reductase, is a cytosolic NADPH-dependent reductase that metabolizes a variety of endogenous compounds, such as aromatic and aliphatic aldehydes and dicarbonyl compounds,...