Family C G-Protein-Coupled Receptors in Alzheimer's Disease and Therapeutic Implications

• Autori principali: Ilaria Dal Prà (Autore), Ubaldo Armato (Autore), Anna Chiarini (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2019-10-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Alzheimer's disease (AD), particularly its sporadic or late-onset form (SAD/LOAD), is the most prevalent (96-98% of cases) neurodegenerative dementia in aged people. AD's neuropathology hallmarks are intrabrain accumulation of amyloid-β peptides (Aβs) and of hyperphosphorylated Tau (p-Tau)...