A Pathway-Based Genetic Score for Oxidative Stress: An Indicator of Host Vulnerability to Phthalate-Associated Adverse Neurodevelopment

• Main Authors: Samuel Tanner (Author), Sarah Thomson (Author), Katherine Drummond (Author), Martin O'Hely (Author), Christos Symeonides (Author), Toby Mansell (Author), Richard Saffery (Author), Peter D. Sly (Author), Fiona Collier (Author), David Burgner (Author), Eva J. Sugeng (Author), Terence Dwyer (Author), Peter Vuillermin (Author), Anne-Louise Ponsonby (Author), on behalf of the Barwon Infant Study Investigator Group (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The developing brain is highly sensitive to environmental disturbances, and adverse exposures can act through oxidative stress. Given that oxidative stress susceptibility is determined partly by genetics, multiple studies have employed genetic scores to explore the role of oxidative stress in human...