Combined Effect of Caspase-Dependent and Caspase-Independent Apoptosis in the Anticancer Activity of Gold Complexes with Phosphine and Benzimidazole Derivatives

• Main Authors: Lara Rouco (Author), Ángeles Sánchez-González (Author), Rebeca Alvariño (Author), Amparo Alfonso (Author), Ezequiel M. Vázquez-López (Author), Emilia García-Martínez (Author), Marcelino Maneiro (Author)
• Format: Book
• Published: MDPI AG, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Since the potential anticancer activity of auranofin was discovered, gold compounds have attracted interest with a view to developing anticancer agents that follow cytotoxic mechanisms other than cisplatin. Two benzimidazole gold(I) derivatives containing triphenylphosphine (Au(pben)(PPh<sub>3...