Trametinib, a MEK1/2 Inhibitor, Protects Mice from Cisplatin- and Noise-Induced Hearing Loss

Hearing loss is one of the most common types of disability; however, there is only one FDA-approved drug to prevent any type of hearing loss. Treatment with the highly effective chemotherapy agent, cisplatin, and exposure to high-decibel noises are two of the most common causes of hearing loss. The...

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Principais autores: Richard D. Lutze (Autor), Matthew A. Ingersoll (Autor), Regina G. Kelmann (Autor), Tal Teitz (Autor)
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Publicado em: MDPI AG, 2024-06-01T00:00:00Z.
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