Insulin alleviates degradation of skeletal muscle protein by inhibiting the ubiquitin-proteasome system in septic rats

• Main Authors: Gao Tao (Author), Yu Wenkui (Author), Tang Shaoqiu (Author), Li Weiqin (Author), Zhu Weiming (Author), Li Ning (Author), Chen Qiyi (Author), Zhang Juanjuan (Author), Li Jieshou (Author)
• Format: Book
• Published: BMC, 2011-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Hypercatabolism is common under septic conditions. Skeletal muscle is the main target organ for hypercatabolism, and this phenomenon is a vital factor in the deterioration of recovery in septic patients. In skeletal muscle, activation of the ubiquitin-proteasome...