Ranolazine: An Old Drug with Emerging Potential; Lessons from Pre-Clinical and Clinical Investigations for Possible Repositioning

• Главные авторы: Sarah Rouhana (Автор), Anne Virsolvy (Автор), Nassim Fares (Автор), Sylvain Richard (Автор), Jérôme Thireau (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2021-12-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Ischemic heart disease is a significant public health problem with high mortality and morbidity. Extensive scientific investigations from basic sciences to clinics revealed multilevel alterations from metabolic imbalance, altered electrophysiology, and defective Ca²⁺/Na<sup...