Structure-Based Screening of Plasmodium berghei Glutathione S-Transferase Identifies CB-27 as a Novel Antiplasmodial Compound

Structure-Based Screening of Plasmodium berghei Glutathione S-Transferase Identifies CB-27 as a Novel Antiplasmodial Compound

Plasmodium falciparum parasites are increasingly drug-resistant, requiring the search for novel antimalarials with distinct modes of action. Enzymes in the glutathione pathway, including glutathione S-transferase (GST), show promise as novel antimalarial targets. This study aims to better understand...

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Main Authors: Emilee E. Colón-Lorenzo (Author), Daisy D. Colón-López (Author), Joel Vega-Rodríguez (Author), Alice Dupin (Author), David A. Fidock (Author), Abel Baerga-Ortiz (Author), José G. Ortiz (Author), Jürgen Bosch (Author), Adelfa E. Serrano (Author)
Format: Book
Published: Frontiers Media S.A., 2020-03-01T00:00:00Z.
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