The Role of Pyrazolo[3,4-d]pyrimidine-Based Kinase Inhibitors in The Attenuation of CCl₄-Induced Liver Fibrosis in Rats

• Main Authors: Diana K. Ghobrial (Author), Nefertiti El-Nikhely (Author), Eman Sheta (Author), Hanan M. Ragab (Author), Sherif A. F. Rostom (Author), Hesham Saeed (Author), Ahmed Wahid (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Liver Fibrosis can be life-threatening if left untreated as it may lead to serious, incurable complications. The common therapeutic approach is to reverse the fibrosis while the intervention is still applicable. Celecoxib was shown to exhibit some antifibrotic properties in the induced fibrotic live...