Design, synthesis, characterization, antimicrobial activity, cytotoxicity, molecular docking, and in-silico ADMET analysis of the novel cefuroxime derivatives

• المؤلفون الرئيسيون: Ananta Kumar Das (مؤلف), Prosenjit Paul (مؤلف), Mahian Parveg Pranto (مؤلف), Md. Jahid Hassan (مؤلف), Koushik Saha (مؤلف), Md. Emdad Hossain (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2024-04-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

This research aims to design and synthesize novel derivatives of Cefuroxime to evaluate their antibacterial effectiveness in comparison to Cefuroxime and to decrease resistance.Schotten Baumann's reaction synthesizes anhydride from acyl chlorides and carboxylate anion. Cefuroxime sodium was rea...