The Functional Polymorphisms of miR-146a Are Associated with Susceptibility to Severe Sepsis in the Chinese Population

• Main Authors: Yiming Shao (Author), Jia Li (Author), Yujie Cai (Author), Yuliu Xie (Author), Guoda Ma (Author), You Li (Author), Yanyan Chen (Author), Gen Liu (Author), Bin Zhao (Author), Lili Cui (Author), Keshen Li (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

MicroRNA-146a (miR-146a) acts as a pivotal regulatory molecule in immune response and various diseases, such as carcinoma and autoimmune diseases. Growing evidences have demonstrated the association of miR-146a gene single-nucleotide polymorphisms (SNPs) with risk of several diseases, but no genetic...