Arsenic trioxide induces ferroptosis in neuroblastoma by mediating GPX4 transcriptional inhibition

• Glavni autori: Mingwei Su (Autor), Xiaoshan Liu (Autor), Yuhan Ma (Autor), Xiaomin Peng (Autor), Xilin Xiong (Autor), Wenjun Weng (Autor), Ke Huang (Autor), Yang Li (Autor)
• Format: Knjiga
• Izdano: Wiley, 2024-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Abstract Neuroblastoma (NB), the most common extracranial solid tumor in childhood, significantly contributes to cancer‐related mortality, presenting a dearth of efficacious treatment strategies. Previously, our studies have substantiated the potent cytotoxicity of arsenic trioxide (ATO) against NB...