Arsenic trioxide induces ferroptosis in neuroblastoma by mediating GPX4 transcriptional inhibition

• Main Authors: Mingwei Su (Author), Xiaoshan Liu (Author), Yuhan Ma (Author), Xiaomin Peng (Author), Xilin Xiong (Author), Wenjun Weng (Author), Ke Huang (Author), Yang Li (Author)
• Format: Book
• Published: Wiley, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Neuroblastoma (NB), the most common extracranial solid tumor in childhood, significantly contributes to cancer‐related mortality, presenting a dearth of efficacious treatment strategies. Previously, our studies have substantiated the potent cytotoxicity of arsenic trioxide (ATO) against NB...