Dec1 Deficiency Ameliorates Pulmonary Fibrosis Through the PI3K/AKT/GSK-3β/β-Catenin Integrated Signaling Pathway

• المؤلفون الرئيسيون: Xingxing Hu (مؤلف), Menglin Zou (مؤلف), Lan Ni (مؤلف), Mingyang Zhang (مؤلف), Weishuai Zheng (مؤلف), Bing Liu (مؤلف), Zhenshun Cheng (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Tissue remodeling/fibrosis is a main feature of idiopathic pulmonary fibrosis (IPF), which results in the replacement of normal lung parenchyma with a collagen-rich extracellular matrix produced by fibroblasts and myofibroblasts. Epithelial-mesenchymal transition (EMT) in type 2 lung epithelial cell...