Suppression of matrix metalloproteinase-9 production from neutrophils by a macrolide antibiotic, roxithromycin, in vitro

• Главные авторы: Ken-Ichi Kanai (Автор), Kazuhito Asano (Автор), Tadashi Hisamitsu (Автор), Harumi Suzaki (Автор)
• Формат: ‌
• Опубликовано: Hindawi Limited, 2004-01-01T00:00:00Z.
• Предметы: article
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BACKGROUND: Macrolide antibiotics such as erythromycin and roxithromycin (RXM) have an anti-inflammatory effect that may account for their clinical benefit in the treatment of chronic airway inflammatory diseases. However, the precise mechanism of this anti-inflammatory effect is not well understood...