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CREB mediates the insulinotropic and anti-apoptotic effects of GLP-1 signaling in adult mouse β-cells

Objective: Glucagon-like peptide-1 (GLP-1) plays a major role in pancreatic β-cell function and survival by increasing cytoplasmic cAMP levels, which are thought to affect transcription through activation of the basic leucine zipper (bZIP) transcription factor CREB. Here, we test CREB function in th...

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Bibliographic Details
Main Authors:	Soona Shin (Author), John Le Lay (Author), Logan J. Everett (Author), Rana Gupta (Author), Kiran Rafiq (Author), Klaus H. Kaestner (Author)
Format:	Book
Published:	Elsevier, 2014-11-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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