In silico drug repositioning based on integrated drug targets and canonical correlation analysis

Abstract Background Besides binding to proteins, the most recent advances in pharmacogenomics indicate drugs can regulate the expression of non-coding RNAs (ncRNAs). The polypharmacological feature in drugs enables us to find new uses for existing drugs (namely drug repositioning). However, current...

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Main Authors: Hailin Chen (Author), Zuping Zhang (Author), Jingpu Zhang (Author)
Format: Book
Published: BMC, 2022-03-01T00:00:00Z.
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3rd Floor Main Library

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