Live Brugia malayi microfilariae inhibit transendothelial migration of neutrophils and monocytes.

• Main Authors: Jan-Hendrik Schroeder (Author), Bigboy H Simbi (Author), Louise Ford (Author), Sara R Cole (Author), Mark J Taylor (Author), Charlotte Lawson (Author), Rachel A Lawrence (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lymphatic filariasis is a major tropical disease caused by the parasite Brugia malayi. Microfilariae (Mf) circulate in the peripheral blood for 2-3 hours in synchronisation with maximal feeding of the mosquito vector. When absent from the peripheral blood, Mf sequester in the capillaries of the lung...