Sulfasalazine Microparticles Targeting Macrophages for the Treatment of Inflammatory Diseases Affecting the Synovial Cavity

• Autori principali: Monica-Carolina (Autore), Ana Fernández-Carballido (Autore), Carolina Hurtado (Autore), Emilia Barcia (Autore), Consuelo Montejo (Autore), Mario Alonso (Autore), Sofia Negro (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2021-06-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Rheumatoid arthritis (RA) is a chronic inflammatory disease with sulfasalazine (SSZ) extensively used for long-term treatment of both juvenile and adult RA. Its use is associated with adverse effects and toxicity due to its non-selective biodistribution. Macrophages play an important role in inflamm...