The Role of P53 in Oral Cancer - A Review

• Main Authors: C Poornima (Author), P G Agnihotri (Author), S Y Rajan (Author), B N Padmavathi (Author), R Guruprasad (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2005-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

P53 is a nuclear phosphoprotein encoded by the tumor suppressor gene p53. This P53 protein plays an important role in the regulation of normal cell proliferation by causing cell cycle arrest. Mutation of p53 gene produces an altered P53 protein leading to loss of cell cycle control. As a result, the...