Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors

• Main Authors: Babu V. Sajesh (Author), Ngoc H. On (Author), Refaat Omar (Author), Samaa Alrushaid (Author), Brian M. Kopec (Author), Wei-Guang Wang (Author), Han-Dong Sun (Author), Ryan Lillico (Author), Ted M. Lakowski (Author), Teruna J. Siahaan (Author), Neal M. Davies (Author), Pema-Tenzin Puno (Author), Magimairajan Issai Vanan (Author), Donald W. Miller (Author)
• Format: Book
• Published: MDPI AG, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The blood-brain barrier (BBB) poses a major obstacle by preventing potential therapeutic agents from reaching their intended brain targets at sufficient concentrations. While transient disruption of the BBB has been used to enhance chemotherapeutic efficacy in treating brain tumors, limitations in t...