Pharmacology of Kappa Opioid Receptors: Novel Assays and Ligands

• Main Authors: Chiara Sturaro (Author), Davide Malfacini (Author), Michela Argentieri (Author), Francine M. Djeujo (Author), Erika Marzola (Author), Valentina Albanese (Author), Chiara Ruzza (Author), Remo Guerrini (Author), Girolamo Calo' (Author), Paola Molinari (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present study investigated the in vitro pharmacology of the human kappa opioid receptor using multiple assays, including calcium mobilization in cells expressing chimeric G proteins, the dynamic mass redistribution (DMR) label-free assay, and a bioluminescence resonance energy transfer (BRET) as...