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Enaminone Modulators of Extrasynaptic α4β3δ γ-Aminobutyric AcidA Receptors Reverse Electrographic Status Epilepticus in the Rat After Acute Organophosphorus Poisoning

Seizures induced by organophosphorus nerve agent exposure become refractory to treatment with benzodiazepines because these drugs engage synaptic γ-aminobutyric acid-A receptors (GABAARs) that rapidly internalize during status epilepticus (SE). Extrasynaptic GABAARs, such as those containing α4β3δ s...

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Egile Nagusiak:	Timothy B. C. Johnstone (Egilea), Hilary S. McCarren (Egilea), Jay Spampanato (Egilea), F. Edward Dudek (Egilea), John H. McDonough (Egilea), Derk Hogenkamp (Egilea), Kelvin W. Gee (Egilea)
Formatua:	Liburua
Argitaratua:	Frontiers Media S.A., 2019-05-01T00:00:00Z.
Gaiak:	article
Sarrera elektronikoa:	Connect to this object online.
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

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