Degenerate sequence-based CRISPR diagnostic for Crimean-Congo hemorrhagic fever virus.

• Main Authors: Hongzhao Li (Author), Alexander Bello (Author), Greg Smith (Author), Dominic M S Kielich (Author), James E Strong (Author), Bradley S Pickering (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

CRISPR (clustered regularly interspaced short palindromic repeats), an ancient defense mechanism used by prokaryotes to cleave nucleic acids from invading viruses and plasmids, is currently being harnessed by researchers worldwide to develop new point-of-need diagnostics. In CRISPR diagnostics, a CR...