An anaplerotic approach to correct the mitochondrial dysfunction in ataxia-telangiectasia (A-T)
Background: ATM, the protein defective in the human genetic disorder, ataxia-telangiectasia (A-T) plays a central role in response to DNA double-strand breaks (DSBs) and in protecting the cell against oxidative stress. We showed that A-T cells are hypersensitive to metabolic stress which can be acco...
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| Main Authors: | , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2021-12-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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Internet
Connect to this object online.3rd Floor Main Library
| Call Number: |
A1234.567 |
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| Copy 1 | Available |