Fluorochloridone induces autophagy in TM4 Sertoli cells: involvement of ROS-mediated AKT-mTOR signaling pathway

• Auteurs principaux: Zhijing Ni (Auteur), Weiqi Sun (Auteur), Rui Li (Auteur), Mingjun Yang (Auteur), Fen Zhang (Auteur), Xiuli Chang (Auteur), Weihua Li (Auteur), Zhijun Zhou (Auteur)
• Format: Livre
• Publié: BMC, 2021-04-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Abstract Background Fluorochloridone (FLC), a selective pyrrolidone herbicide, has been recognized as a potential endocrine disruptor and reported to induce male reproductive toxicity, but the underlying mechanism is unclear. The aim of this study was to investigate the mechanism of FLC-induced repr...