Fluorochloridone induces autophagy in TM4 Sertoli cells: involvement of ROS-mediated AKT-mTOR signaling pathway

• Main Authors: Zhijing Ni (Author), Weiqi Sun (Author), Rui Li (Author), Mingjun Yang (Author), Fen Zhang (Author), Xiuli Chang (Author), Weihua Li (Author), Zhijun Zhou (Author)
• Format: Book
• Published: BMC, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Fluorochloridone (FLC), a selective pyrrolidone herbicide, has been recognized as a potential endocrine disruptor and reported to induce male reproductive toxicity, but the underlying mechanism is unclear. The aim of this study was to investigate the mechanism of FLC-induced repr...