Effect of Selective Cysteinyl Leukotriene Receptor Antagonists on Airway Inflammation and Matrix Metalloproteinase Expression in a Mouse Asthma Model

• Main Authors: Chia-Hsiu Hsu (Author), Chun-Ming Hu (Author), Ko-Hsiu Lu (Author), Shun-Fa Yang (Author), Chung-Hung Tsai (Author), Chun-Liang Ko (Author), Hai-Lun Sun (Author), Ko-Huang Lue (Author)
• Format: Book
• Published: Elsevier, 2012-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cysteinyl leukotrienes (CysLTs) play a major role in the pathogenic changes of airway inflammation in asthma treatment. The matrix metalloproteinase (MMP) family, especially MMP-9 and MMP-2 levels, can reflect the status of airway remodeling. This study was undertaken to determine the role of a spec...