Behavioral and pharmacological characteristics of bortezomib-induced peripheral neuropathy in rats

• Main Authors: Shota Yamamoto (Author), Takehiro Kawashiri (Author), Hitomi Higuchi (Author), Kuniaki Tsutsumi (Author), Soichiro Ushio (Author), Takanori Kaname (Author), Masafumi Shirahama (Author), Nobuaki Egashira (Author)
• Format: Book
• Published: Elsevier, 2015-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bortezomib, an effective anticancer drug for multiple myeloma, often causes peripheral neuropathy which is mainly characterized by numbness and painful paresthesia. Nevertheless, there is no effective strategy to escape or treat bortezomib-induced peripheral neuropathy (BIPN), because we have unders...