Antioxidant Synergy of Mitochondrial Phospholipase PNPLA8/iPLA2γ with Fatty Acid-Conducting SLC25 Gene Family Transporters

• Hauptverfasser: Martin Jabůrek (Verfasst von), Pavla Průchová (Verfasst von), Blanka Holendová (Verfasst von), Alexander Galkin (Verfasst von), Petr Ježek (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2021-04-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Patatin-like phospholipase domain-containing protein PNPLA8, also termed Ca²⁺-independent phospholipase A2γ (iPLA2γ), is addressed to the mitochondrial matrix (or peroxisomes), where it may manifest its unique activity to cleave phospholipid side-chains from both sn-1 and sn-2...