Characterization of Novel Dipeptidyl Peptidase-IV Inhibitory Peptides from Soft-Shelled Turtle Yolk Hydrolysate Using Orthogonal Bioassay-Guided Fractionations Coupled with In Vitro and In Silico Study

• Main Authors: Nhung Thi Phuong Nong (Author), Yu-Kuo Chen (Author), Wen-Ling Shih (Author), Jue-Liang Hsu (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2020-10-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Five novel peptides (LPLF, WLQL, LPSW, VPGLAL, and LVGLPL) bearing dipeptidyl peptidase IV (DPP-IV) inhibitory activities were identified from the gastrointestinal enzymatic hydrolysate of soft-shelled turtle yolk (SSTY) proteins. Peptides were isolated separately using reversed-phase (RP) chromatog...