The validity of immunohistochemistry in detecting microsatellite instability in pediatric solid neoplasms

• Main Authors: Khaldoon Aljerian (Author), Waleed AlRajban (Author), Tariq Aljohani (Author), Ali Alshehri (Author), Omar Alsherif (Author), Musa Alharbi (Author), Ibraheem Abosoudah (Author), Wasil Jastaniah (Author), Saad Al Daama (Author), Abdulrahman AlSultan (Author), Nahaa Eid Alsubaie (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The DNA mismatch repair (MMR) is the biological pathway that plays a key role in maintaining genomic stability during DNA replication and recombination. The value of MMR pathway is under investigation in pediatrics' solid tumors. Aims: In this research work, we investigated the prot...