Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor response
Early success with brentuximab vedotin in treating classical Hodgkin lymphoma spurred an influx of at least 20 monomethyl auristatin E (MMAE) antibody-drug conjugates (ADCs) into clinical trials. While three MMAE-ADCs have been approved, most of these conjugates are no longer being investigated in c...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Book |
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Taylor & Francis Group,
2021-01-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |