Preclinical optimization of Ly6E-targeted ADCs for increased durability and efficacy of anti-tumor response

Early success with brentuximab vedotin in treating classical Hodgkin lymphoma spurred an influx of at least 20 monomethyl auristatin E (MMAE) antibody-drug conjugates (ADCs) into clinical trials. While three MMAE-ADCs have been approved, most of these conjugates are no longer being investigated in c...

Full description

Saved in:
Bibliographic Details
Main Authors: Josefa Dela Cruz Chuh (Author), MaryAnn Go (Author), Yvonne Chen (Author), Jun Guo (Author), Hanine Rafidi (Author), Danielle Mandikian (Author), Yonglian Sun (Author), Zhonghua Lin (Author), Kellen Schneider (Author), Pamela Zhang (Author), Rajesh Vij (Author), Danielle Sharpnack (Author), Pamela Chan (Author), Cecile de la Cruz (Author), Jack Sadowsky (Author), Dhaya Seshasayee (Author), James T. Koerber (Author), Thomas H. Pillow (Author), Gail D. Phillips (Author), Rebecca K Rowntree (Author), C. Andrew Boswell (Author), Katherine R. Kozak (Author), Andrew G. Polson (Author), Paul Polakis (Author), Shang-Fan Yu (Author), Peter S. Dragovich (Author), Nicholas J. Agard (Author)
Format: Book
Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available