Mycobacterium leprae-Infected Macrophages Preferentially Primed Regulatory T Cell Responses and Was Associated with Lepromatous Leprosy.

• Main Authors: Degang Yang (Author), Tiejun Shui (Author), Jake W Miranda (Author), Danny J Gilson (Author), Zhengyu Song (Author), Jia Chen (Author), Chao Shi (Author), Jianyu Zhu (Author), Jun Yang (Author), Zhichun Jing (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:The persistence of Mycobacterium leprae (M. leprae) infection is largely dependent on the types of host immune responses being induced. Macrophage, a crucial modulator of innate and adaptive immune responses, could be directly infected by M. leprae. We therefore postulated that M. leprae-...