Pharmacokinetic Study of Oral 14C-Radiolabeled Hyzetimibe, A New Cholesterol Absorption Inhibitor
Background and objectives: Hyzetimibe is a candidate drug being investigated as the second-in-class cholesterol absorption inhibitor; it lowers plasma levels of low-density lipoprotein cholesterol (LDL-C) by blocking the Niemann-Pick C1-like 1 protein, a transporter mainly expressed in the intestine...
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Main Authors: | Jianwei Liao (Author), Xin Wang (Author), Zhenyu Li (Author), Dongsheng Ouyang (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2021-05-01T00:00:00Z.
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