Concomitant novel ALK-SSH2, EML4-ALK and ARID2-ALK, EML4-ALK double-fusion variants and confer sensitivity to crizotinib in two lung adenocarcinoma patients, respectively

Abstract Introduction Anaplastic lymphoma kinase (ALK) gene rearrangements, have been identified in approximately 2-7% of patients with lung adenocarcinoma (LUAD). However, co-occurrence of double ALK fusions in one patient was rare. Herein, we reported two Chinese female LUAD patients with confirme...

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Main Authors: Hong Tao (Author), Zhe Liu (Author), Jing Mu (Author), Fei Gai (Author), Zhan Huang (Author), Liang Shi (Author)
Format: Book
Published: BMC, 2022-02-01T00:00:00Z.
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