Evidence for the anti-NAFLD effectiveness of chlorogenic acid as a HAT inhibitor using in vivo experiments supported by virtual molecular docking

• Main Authors: Jing Xu (Author), Liangqin Gao (Author), Huiqing Liang (Author), Shaoliang Zhang (Author), Penghua Lai (Author), Shaodong Chen (Author)
• Format: Book
• Published: Elsevier, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hypothesis: Targeted histone acetyltransferase (HAT) may screen out phytomedicine for the treatment of nonalcoholic fatty liver disease (NAFLD) Study Design: In this study, the transcriptional co-activator p300, a type of HAT, was used as a ligand for virtual molecular docking to screen small molecu...