Effectiveness of miltefosine in cutaneous leishmaniasis caused by Leishmania tropica in Pakistan after antimonial treatment failure or contraindications to first line therapy-A retrospective analysis.

• Main Authors: Suzette Kämink (Author), Boota Masih (Author), Noor Ali (Author), Aman Ullah (Author), Syed Juma Khan (Author), Shakil Ashraf (Author), Tetyana Pylypenko (Author), Martin P Grobusch (Author), Jena Fernhout (Author), Margriet den Boer (Author), Koert Ritmeijer (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Cutaneous leishmaniasis (CL) is a neglected tropical skin disease, caused by Leishmania protozoa. In Pakistan, where CL caused by L. tropica is highly endemic, therapy with pentavalent antimonials is the standard of care, but has significant toxicity when used in syste...