Epigenetic and parasitological parameters are modulated in EBi3-/- mice infected with Schistosoma mansoni.

• Main Authors: Ester Alves Mota (Author), Andressa Barban do Patrocínio (Author), Vanderlei Rodrigues (Author), João Santana da Silva (Author), Vanessa Carregaro Pereira (Author), Renata Guerra-Sá (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Schistosoma mansoni adaptive success is related to regulation of replication, transcription and translation inside and outside the intermediate and definitive host. We hypothesize that S. mansoni alters its epigenetic state in response to the mammalian host immune system, reprogramming gene expressi...