Chemistry and Pharmacology of Fluorinated Drugs Approved by the FDA (2016-2022)

• Main Authors: Ghulam Shabir (Author), Aamer Saeed (Author), Wajeeha Zahid (Author), Fatima Naseer (Author), Zainab Riaz (Author), Nafeesa Khalil (Author), Muneeba (Author), Fernando Albericio (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fluorine is characterized by high electronegativity and small atomic size, which provide this molecule with the unique property of augmenting the potency, selectivity, metabolic stability, and pharmacokinetics of drugs. Fluorine (F) substitution has been extensively explored in drug research as a me...