Mitigated suppressive function of regulatory T cells (Treg) upon Th17-inducing cytokines in oligo- and polyarticular Juvenile Idiopathic Arthritis (JIA) patients

• Główni autorzy: Marie-Therese Holzer (Autor), Giovanni Almanzar (Autor), Robert Woidich (Autor), Boris Hügle (Autor), Johannes-Peter Haas (Autor), Martina Prelog (Autor)
• Format: Książka
• Wydane: BMC, 2022-04-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract Background The plasticity of T helper-17 (Th17) and regulatory T (Treg) cells may be a clue to pathogenesis of Juvenile Idiopathic Arthritis (JIA). It is still unclear, whether targeted suppression of Interleukin (IL)-17 is able to influence regulatory function of Treg to control pro-inflam...