Brush swab as a noninvasive surrogate for tissue biopsies in epigenomic profiling of oral cancer

• Main Authors: Chi T. Viet (Author), Xinyu Zhang (Author), Ke Xu (Author), Gary Yu (Author), Kesava Asam (Author), Carissa M. Thomas (Author), Nicholas F. Callahan (Author), Coleen Doan (Author), Paul C. Walker (Author), Khanh Nguyen (Author), Stephanie C. Kidd (Author), Steve C. Lee (Author), Anupama Grandhi (Author), Clint T. Allen (Author), Simon Young (Author), James C. Melville (Author), Jonathan W. Shum (Author), Dan T. Viet (Author), Alan S. Herford (Author), Dylan F. Roden (Author), Manuel L. Gonzalez (Author), Jiang F. Zhong (Author), Bradley E. Aouizerat (Author)
• Format: Book
• Published: BMC, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Oral squamous cell carcinoma (OSCC) has poor survival rates. There is a pressing need to develop more precise risk assessment methods to tailor clinical treatment. Epigenome-wide association studies in OSCC have not produced a viable biomarker. These studies have relied on methyl...