Development, Characterization, and Pharmacokinetic Evaluation of a CRV431 Loaded Self-Microemulsifying Drug Delivery System

PURPOSE: The objective of this study was to develop a self-microemulsifying drug delivery system (SMEDDS) formulation for the oral delivery of CRV431, a non-immunosuppressive analogue of cyclosporine A. Relative to cyclosporine A, CRV431 is poorly soluble in lipid solvents and thusly presents a chal...

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Main Authors: Daniel J Trepanier (Author), Daren R Ure (Author), Robert Thomas Foster (Author)
Formato: Libro
Publicado: Frontiers Media S.A., 2018-11-01T00:00:00Z.
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Número de Clasificación: A1234.567
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