Coptisine Induces Apoptosis in Human Hepatoma Cells Through Activating 67-kDa Laminin Receptor/cGMP Signaling

• Main Authors: Li Zhou (Author), Fan Yang (Author), Guobing Li (Author), Jingbin Huang (Author), Yali Liu (Author), Qian Zhang (Author), Qin Tang (Author), Changpeng Hu (Author), Rong Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hepatocellular carcinoma (HCC) is the most common primary cancer of the liver. Hence, new anti-liver cancer treatment strategies need to be urgently developed. Coptisine is a natural alkaloid extracted from rhizoma coptidis which exhibits anticancer activity in various preclinical models, including...