Dual inhibition of TMPRSS2 and Cathepsin Bprevents SARS-CoV-2 infection in iPS cells

• Main Authors: Rina Hashimoto (Author), Ayaka Sakamoto (Author), Sayaka Deguchi (Author), Renxing Yi (Author), Emi Sano (Author), Akitsu Hotta (Author), Kazutoshi Takahashi (Author), Shinya Yamanaka (Author), Kazuo Takayama (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

It has been reported that many receptors and proteases are required for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. Although angiotensin-converting enzyme 2 (ACE2) is the most important of these receptors, little is known about the contribution of other genes. In this stu...