The Neonatal and Juvenile Pig in Pediatric Drug Discovery and Development

• Main Authors: Miriam Ayuso (Author), Laura Buyssens (Author), Marina Stroe (Author), Allan Valenzuela (Author), Karel Allegaert (Author), Anne Smits (Author), Pieter Annaert (Author), Antonius Mulder (Author), Sebastien Carpentier (Author), Chris Van Ginneken (Author), Steven Van Cruchten (Author)
• Format: Book
• Published: MDPI AG, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pharmacotherapy in pediatric patients is challenging in view of the maturation of organ systems and processes that affect pharmacokinetics and pharmacodynamics. Especially for the youngest age groups and for pediatric-only indications, neonatal and juvenile animal models can be useful to assess drug...