The impacts of natural product miltirone and the CYP2D6 pharmacogenetic phenotype on fluoxetine metabolism

• Autors principals: Xiaodan Zhang (Autor), Qingqing Li (Autor), Xinwu Ye (Autor), Qing Chen (Autor), Chen Chen (Autor), Guoxin Hu (Autor), Likang Zhang (Autor), Lianguo Chen (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2024-04-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Introduction: To study the effects of drug-induced CYP2D6 activity inhibition and genetic polymorphisms on fluoxetine metabolism, rat liver microsomes (RLMs) and SD rats were used to investigate the potential drug‒drug interactions (DDIs), and CYP2D6 http://muchong.com/t-10728934-1 recombinant bacul...