Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK)

• প্রধান লেখক: Xueqin Huang (লেখক), Li You (লেখক), Eugenie Nepovimova (লেখক), Miroslav Psotka (লেখক), David Malinak (লেখক), Marian Valko (লেখক), Ladislav Sivak (লেখক), Jan Korabecny (লেখক), Zbynek Heger (লেখক), Vojtech Adam (লেখক), Qinghua Wu (লেখক), Kamil Kuca (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Phosphoinositide 3-kinases (PI3K) and phosphoinositide 3-kinase-related protein kinases (PIKK) are two structurally related families of kinases that play vital roles in cell growth and DNA damage repair. Dysfunction of PIKK members and aberrant stimulation of the PI3K/AKT/mTOR signalling pathway are...