Neuregulin 1 regulates amyloid precursor protein cell surface expression and non-amyloidogenic processing

• Asıl Yazarlar: Young-Jung Kim (Yazar), Ji-Young Yoo (Yazar), Ok-Soon Kim (Yazar), Han-byeol Kim (Yazar), Junghwa Ryu (Yazar), Hye-Sun Kim (Yazar), Jun-Ho Lee (Yazar), Hong-Il Yoo (Yazar), Dae-Yong Song (Yazar), Tai-Kyoung Baik (Yazar), Ran-Sook Woo (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2018-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The amyloid precursor protein (APP) is a key molecule in Alzheimer's disease. The prevailing view is that APP is initially transported to the plasma membrane as a full-length protein. Its localization at the cell surface can trigger downstream signaling and APP cleavage. Our previous work has s...