Changes in Gene Expression Profiling and Phenotype in Aged Multidrug Resistance Protein 4-Deficient Mouse Retinas

• Main Authors: Kyung Woo Kim (Author), Sentaro Kusuhara (Author), Atsuko Katsuyama-Yoshikawa (Author), Sho Nobuyoshi (Author), Megumi Kitamura (Author), Sotaro Mori (Author), Noriyuki Sotani (Author), Kaori Ueda (Author), Wataru Matsumiya (Author), Akiko Miki (Author), Takuji Kurimoto (Author), Hisanori Imai (Author), Makoto Nakamura (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Multidrug resistance protein 4 (MRP4) is an energy-dependent membrane transporter responsible for cellular efflux of a broad range of xenobiotics and physiological substrates. In this trial, we aimed to investigate the coeffects of aging and MRP4 deficiency using gene expression microarray and morph...