CD44 Suppression Improved the Chemosensitivity of HT-29 Colorectal Cancer Cells to 5-Fluorouracil and Inhibited Cell Migration

• Main Authors: Souzan Najafi (Author), Zohreh Rahimi (Author), Behzad Mansoori (Author), Ali Mohammadi (Author), Fatemeh Mohammadnejad (Author), Mohammad Amini (Author), Ahad Mokhtazadeh (Author), Zahra Asadzadeh (Author), William Chi-Shing Cho (Author), Behzad Baradaran (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: CD44 plays a pivotal role through tumorigenesis by regulating cancer cell metastasis, stemness, and chemosensitivity and is considered a promising therapeutic target for human cancers, including colorectal cancer (CRC). Therefore, the present research aimed to examine the simultaneous thera...